Kliofem Tablets

What is Kliofem?

Kliofem is a type of hormone replacement therapy (HRT) used to treat symptoms of menopause in postmenopausal women.  It contains:

• Estradiol (2 mg): Identical to the estrogen hormone produced by the ovaries.
• Norethisterone acetate 1mg: A synthetic progestogen that mimics the effects of natural progesterone in the body.

It comes in the form of combined HRT treatment tablets that are taken orally every day without interruption. Kliofem helps relieve unpleasant menopause symptoms by replacing diminishing estrogen levels and balancing out the hormones in women after menopause.

What is Kliofem used for?

Kliofem tablets have two main uses:

Relieve Menopausal Symptoms: Take HRT medications like Kliofem to relieve moderate to severe menopause symptoms that hinder daily life, such as:

• Hot flashes and night sweats
• Vaginal dryness and discomfort
• Mood changes like depression and irritability
• Difficulty sleeping
• Reduced sex drive

Prevention of Osteoporosis: Estrogen plays a key role in maintaining healthy bones. Declining estrogen after menopause can lead to weak and fragile bones, increasing the risk of fractures.

Kliofem helps prevent osteoporosis in postmenopausal women with additional risk factors, provided other osteoporosis medications are unsuitable.

How does Kliofem work?

Kliofem contains synthetic versions of estrogen and progestogen, which mimic the hormones naturally produced by the ovaries. This medication works as hormone replacement therapy to relieve menopausal symptoms with the help of active ingredients in two key ways.

The estrogen component helps reduce hot flashes and night sweats, alleviates vaginal dryness, improves sleep quality, and enhances irregular mood. Meanwhile, the progesterone component plays a crucial role in balancing estrogen levels in the endometrium (uterine lining) and reducing the risk of endometrial hyperplasia. 

By replenishing diminishing levels of estrogen and progesterone in the body, Kliofem helps restore hormonal balance and alleviate discomfort associated with menopause.

Alternatives to Kliofem

Some alternatives for managing menopause symptoms and preventing osteoporosis include:

For Symptom Relief

• Vaginal estrogen creams
• Antidepressants
• Gabapentin
• Clonidine
• Cognitive behavioral therapy

For Osteoporosis Prevention

• Bisphosphonates like alendronate
• Denosumab
• Raloxifene
• Strontium ranelate
• Calcium and vitamin D

Your GP can help determine if these alternative options may be more suitable for women whose health conditions require a different approach.

Kliofem reviews

Based on patient experiences, Kliofem can help relieve hot flashes, night sweats, mood changes, and sleep disturbances.

Here are some of the reviews:

"I have been taking it now for 8 months after no period for over a year.. I did have some fairly irregular bleeding for the first 2 months ( for the last 2 weeks of each pack) but nothing since then. The hot flushes and sweats stopped in less than 10 days." - Munchyseeds

"I've been on HRT for 11 years, am in my early 60s and have not put weight on. In fact a few years into using HRT I lost 5 lbs that had crept on. I have however, cut down on the amount I eat because our metabolism changes post menopause anyway. I am also far less active compared to how I was years ago when I was either working in a busy job, dashing about, or running after my kids!" - JinglingHellsBells

Patient Information Leaflet

The effects of Kliofem vary from person to person. The patient information leaflet containing uses, dosage, side effects, and other drug information can be found here.